Misa is a short, slender, attractive young woman with long, straight, golden-blonde hair, most commonly styled with a portion of her hair in pigtails tied with red bands, but occasionally worn loose as well. In the anime, it seems that she was a brunette at one point.[4] In the manga, her eyes are predominantly light brown; however, they have also been shown as green. She also often wears blue contact lenses. In the games, her eyes are usually light brown but have also been seen as pink. Misa also appears to have black hair in the movie, which she was wearing in pigtails throughout the film.

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