|the "Genetic alterations", such as chromosomal alterations and specific genetic


|the "Genetic alterations", such as chromosomal alterations and specific genetic mutations, or how the presence of an additional chromosome as in Down syndrome or when there is a substitution of a single base pair that determines an amino acid situation as occurs in the case of sickle cell disease, which can give rise to clinical phenotypes in the form of congenital malformations or anemias, genetic defects, These genetic alterations are the cause of cellular damage.
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|the "Genetic alterations"
,
such as chromosomal alterations and specific genetic mutations
,
or how the presence of an additional chromosome as in Down syndrome or when there is a substitution of a single base pair that determines an amino acid situation as occurs in the case of sickle cell disease
,
which can give rise to clinical phenotypes in the form of congenital malformations or anemias
,
genetic defects
,
These genetic alterations are the cause of cellular damage
.
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